Washington, D.C. 20549
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): May 15, 2023
(Exact name of registrant as specified in its charter)
Delaware 001-40646 85-3383487
(State or other jurisdiction
of incorporation)
File Number)
(I.R.S. Employer
Identification No.)
18105 SE Mill Plain Blvd
Vancouver, WA 98683
(Address of principal executive offices, including zip code)
(360) 949-1041
(Registrant’s telephone number, including area code)
Not Applicable
(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.0001 par value per shareABSIThe Nasdaq Global Select Market
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company  
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  

Item 2.02.     Results of Operations and Financial Condition.

On May 15, 2023, Absci Corporation (the “Company”) announced its financial results for the first quarter ended March 31, 2023. A copy of the press release is being furnished as Exhibit 99.1 to this Current Report on Form 8-K.

The information contained in Item 2.02 of this Current Report on Form 8-K is being furnished and shall not be deemed to be “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section and shall not be incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

Item 9.01.    Financial Statements and Exhibits.
(d) Exhibits
99.1     Press Release issued by the Company on May 15, 2023, furnished herewith.

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Absci Corporation
Date: May 15, 2023
/s/ Sean McClain
Sean McClain
Founder and CEO

Exhibit 99.1

Absci Reports Business Updates and First Quarter 2023 Financial and Operating Results

Commenced work plan preparations and expect to initiate program work during second quarter leveraging Absci's generative AI drug creation platform for Phase II candidate

Achieved rapid advancements of generative AI drug creation platform, continually building on prior breakthroughs
VANCOUVER, Wash. and NEW YORK, May 15, 2023 – Absci Corporation (Nasdaq: ABSI), a generative AI drug creation company, today reported financial and operating results for the quarter ended March 31, 2023.
"With our Integrated Drug CreationTM platform and our team's unprecedented rate of innovation this year, we have achieved multiple industry breakthroughs and further demonstrated our position as a leader in the field of AI drug discovery," said Sean McClain, Founder and CEO. "Our ability to rapidly advance our models and platform and accelerate our pace of innovation has been illustrated through the manuscripts we have published this year demonstrating successive enhancements of our platform, and through new partnerships and programs initiated. This accelerated progress has been instrumental as we continue to advance and expand external partnership discussions, in addition to the meaningful advancements we have made on our internal pipeline of assets."
"We believe our platform offers multiple unique capabilities, enabling a shorter time to reach IND and delivering differentiated antibody compositions as well as the ability to unlock undruggable targets. Combined with key data and development partnerships, Absci is poised to rapidly grow our strategic portfolio across a range of therapeutic areas — and achieve our mission of creating better biologics for patients, faster."
Recent Highlights
Commenced work plan preparations and expecting to initiate program work in the second quarter leveraging Absci's generative AI drug creation platform capabilities to optimize pharmacokinetic properties for a Phase II candidate with an undisclosed partner announced in March 2023.
Entered into partnership with the University of Oxford’s Kennedy Institute of Rheumatology, a biomedical research center developing new therapies for chronic inflammatory and musculoskeletal conditions, to create breakthrough therapies for immune-mediated diseases. Through this partnership, Absci will apply its generative AI platform to The Kennedy Institute’s immunology biorepository to speed the discovery and development of multiple therapies.

Exhibit 99.1
Entered into partnership with Aster Insights (formerly M2GEN), an oncology bioinformatics company, to create new cancer medicines and bring them to market at unprecedented speed. Through this partnership, Absci’s generative AI drug creation platform will tap into Aster Insights's clinical and molecular data set, ORIEN AVATAR®, to accelerate the creation of therapeutics for a range of malignancies and patient profiles, bringing AI drug creation to the fight against cancer.
Continued adding talent to growing AI team, now including experience from OpenAI, Meta, Tesla, Google Brain, Roivant, Encoded Therapeutics, and Dyno Therapeutics, among others.
Achieved industry breakthrough as the first to design and validate de novo therapeutic antibodies with zero-shot generative AI. This breakthrough unlocks the potential to accelerate time to clinic by over 50% and increase probability of success in the clinic. Absci’s zero-shot model generates antibody designs that are unlike those found in existing antibody databases, in cycle times as little as six weeks, including de novo versions of all three heavy chain CDRs (HCDR123). The data published also demonstrates the effectiveness of Absci’s generative AI platform at generating de novo antibodies that bind to the target of interest, with a hit rate up to five to 30 times greater than biological baselines examined.
First Quarter 2023 Financial Results
Revenue was $1.3 million for the three months ended March 31, 2023 compared to $0.8 million for the three months ended March 31, 2022. This increase was driven by partnered program mix and progress timing. Revenue in the first quarter of 2023 was impacted by timing of progress on the Merck research collaboration based on administrative delays, and Absci expects to recognize revenues from this collaboration throughout 2023.
Research and development expenses were $12.7 million for the first quarter of 2023 compared to $15.8 million for the corresponding prior year period. This decrease was primarily driven by lower laboratory operational costs.
Selling, general, and administrative expenses were $9.6 million for the first quarter of 2023 compared to $10.9 million for the corresponding prior year period. This decrease was primarily due to a reduction in insurance costs.
Net loss was $23.4 million for the first quarter of 2023, as compared to $29.5 million for the corresponding prior year period.
Cash, cash equivalents, and short-term investments as of March 31, 2023 was $144.3 million, compared to $164.4 million as of December 31, 2022.

Exhibit 99.1
2023 Outlook
Absci continues to anticipate at least ten new Active Programs in 2023, based on the company's current partnership pipeline. Absci also expects to generate more cash from execution on partnered programs this year and going forward, as compared to prior years, given the shift from cell line development to discovery programs.
Absci continues to expect a gross use of cash, cash equivalents, and short-term investments, exclusive of partnered program and equipment financing receipts, of approximately $90 million, below prior year use of $105 million. Absci also continues to focus its investments and operations on strategic initiatives and near-term inflection points, providing cash and cash equivalents and short-term investments into late 2025, consistent with previous disclosures.
About Absci
Absci is a generative AI drug creation company that combines AI with scalable wet lab technologies to create better biologics for patients, faster. Our Integrated Drug Creation™ platform unlocks the potential to accelerate time to clinic and increase the probability of success by simultaneously optimizing multiple drug characteristics important to both development and therapeutic benefit. With the data to learn, the AI to create, and the wet lab to validate, we can screen billions of cells per week, allowing us to go from AI-designed antibodies to wet lab-validated candidates in as little as six weeks. Our vision is to deliver breakthrough therapeutics at the click of a button, for everyone. Absci’s headquarters is in Vancouver, WA, with our AI Research Lab in New York City and an Innovation Center in Zug, Switzerland. Visit www.absci.com and follow us on LinkedIn (@absci), Twitter (@Abscibio), and YouTube.
Availability of Other Information About Absci
Investors and others should note that we routinely communicate with investors and the public using our website (www.absci.com) and our investor relations website (investors.absci.com), including without limitation, through the posting of investor presentations, SEC filings, press releases, public conference calls and webcasts on these websites, as well as on Twitter, LinkedIn and YouTube. The information that we post on these websites and social media outlets could be deemed to be material information. As a result, investors, the media, and others interested in Absci are encouraged to review this information on a regular basis. The contents of our website and social media postings, or any other website that may be accessed from our website or social media postings, shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended.
Forward-Looking Statements
Certain statements in this press release that are not historical facts are considered forward-looking within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities

Exhibit 99.1
Exchange Act of 1934, as amended, including statements containing the words “will,” “pursues,” “anticipates,” “plans,” “believes,” “forecast,” “potential,” “estimates,” “extends,” “expects,” and “intends,” or similar expressions. We intend these forward-looking statements, including statements regarding our expectations regarding business operations, financial performance, and results of operations, including our expectations and guidance regarding cash, cash equivalents, and short-term investments, our projected cash usage, needs, and runway, our expectations regarding the timing of regulatory filings related to our programs and the count of new Active Programs, our technology development efforts and the application of those efforts, including accelerating drug development timelines, increasing probability of successful drug development, advancing toward in silico drug design, our drug discovery and development activities related to partnered programs and our internal therapeutic assets, and our internal research and publication efforts, to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act and Section 21E of the Securities Exchange Act, and we make this statement for purposes of complying with those safe harbor provisions. These forward-looking statements reflect our current views about our plans, intentions, expectations, strategies, and prospects, which are based on the information currently available to us and on assumptions we have made. We can give no assurance that the plans, intentions, expectations, or strategies will be attained or achieved, and, furthermore, actual results may differ materially from those described in the forward-looking statements and will be affected by a variety of risks and factors that are beyond our control, including, without limitation, risks and uncertainties relating to our ability to effectively collaborate on research, drug discovery, and development activities with our partners or potential partners and challenges inherent in discovery and development of therapeutic assets; along with those risks set forth in our most recent periodic report filed with the U.S. Securities and Exchange Commission, as well as discussions of potential risks, uncertainties, and other important factors in our subsequent filings with the U.S. Securities and Exchange Commission. Except as required by law, we assume no obligation to update publicly any forward-looking statements, whether as a result of new information, future events, or otherwise.
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Exhibit 99.1
Absci Corporation
Unaudited Condensed Consolidated Statements of Operations

For the Three Months Ended March 31,
(In thousands, except for share and per share data)20232022
Technology development revenue$1,269 $454 
Collaboration revenue— 365 
Total revenues1,269 819 
Operating expenses
Research and development12,657 15,827 
Selling, general and administrative9,593 10,889 
Depreciation and amortization3,504 2,906 
Total operating expenses25,754 29,622 
Operating loss(24,485)(28,803)
Other income (expense)
Interest expense(321)(195)
Other income, net1,458 125 
Total other income (expense), net1,137 (70)
Loss before income taxes(23,348)(28,873)
Income tax expense(7)(621)
Net loss$(23,355)$(29,494)
Net loss per share:
Basic and diluted
Weighted-average common shares outstanding:
Basic and diluted
91,479,452 90,272,205 

Exhibit 99.1
Absci Corporation
Unaudited Condensed Consolidated Balance Sheets
March 31,December 31,
(In thousands, except for share and per share data)20232022
Current assets:
Cash and cash equivalents$11,409 $59,955 
Restricted cash15,027 15,023 
Short-term investments132,849 104,476 
Receivables under development arrangements, net1,326 1,550 
Prepaid expenses and other current assets4,706 5,859 
Total current assets165,317 186,863 
Operating lease right-of-use assets5,106 5,319 
Property and equipment, net50,166 52,723 
Intangibles, net50,780 51,622 
Goodwill21,335 21,335 
Restricted cash, long-term1,882 1,864 
Other long-term assets1,222 1,282 
TOTAL ASSETS$295,808 $321,008 
Current liabilities:
Accounts payable$1,933 $2,412 
Accrued expenses18,089 20,481 
Long-term debt3,078 2,946 
Operating lease obligations1,712 1,690 
Financing lease obligations2,030 2,296 
Deferred revenue359 445 
Total current liabilities27,201 30,270 
Long-term debt - net of current portion7,190 7,984 
Operating lease obligations - net of current portion6,881 7,317 
Finance lease obligations - net of current portion347 750 
Deferred tax, net224 238 
Other long-term liabilities— 35 
Preferred stock, $0.0001 par value— — 
Common stock, $0.0001 par value
Additional paid-in capital573,335 570,454 
Accumulated deficit(319,284)(295,929)
Accumulated other comprehensive loss(95)(120)